The results of the meta-analysis revealed that vitamin D supplementation in women with PCOS did not have significant effect on total testosterone (SMD: −0.18, 95% CI: −0.37, 0.02; Figure 7(a)), DHEAS (SMD: −0.02, 95% CI: −0.27, 0.22; Figure 7(b)), and SHBG (SMD: 0.37, 95% CI: −0.39, 1.13; Figure 7(c)). The gene discussed is SHBG; the disease is polycystic ovary syndrome.