STC1 and colonic neoplasm: Stanniocalcin-1 (STC1) is a secreted glycoprotein whose increasing expression is linked to poor prognosis, progression, and metastasis of a variety of tumors, such as breast cancer (Chang et al., 2015), ovarian cancer (Zhang C. et al., 2019), and colon cancer (Pena et al., 2013).