NLRP3 inflammasome signaling is implicated in the onset of a number of diseases, including gout (24), atherosclerosis (23), type ІІ diabetes (42, 43), Cryopyrin-associated periodic syndrome (CAPS) (44), various types of cancer (45), and inflammatory bowel disease (IBD) (46). The gene discussed is NLRP3; the disease is cryopyrin-associated periodic syndrome.