TSC22D3 and Sepsis: Although the immune system changes as sepsis progresses, GILZ expression is stable during the late stage of inflammation, especially during immunosuppression, which is probably due to GILZ acting as a downstream molecule and regulation by endogenous cortisol in vivo. Hence, GILZ might become a potential monitoring molecule under the regulation of endogenous glucocorticoids or guide treatment with glucocorticoids.