Similarly, ILC3s that are NKp46-CCR6-/low are able to differentiate into NKp46+ ILC3s, depending on upregulation of the prototypic ILC1 transcription factor, T-bet, which stimulates IFNγ and IL-22 production that are important for protection against Salmonella infection (10). Here, NCR1 is linked to Salmonella Infections.