The patient experienced grade 2 CRS with the peak concentrations of IL-6, IFN-γ and IL-10 being 539.14 pg/mL, 12.48 pg/mL and 36.48 pg/mL on day 7 after the 2nd infusion, respectively (Figures 4A–D). The gene discussed is IL6; the disease is congenital rubella syndrome.