The analysis of TCGA RNA-seq data using the TIMER database (http://cistrome.org/TIMER/) showed that ERLIN2 mRNA expression was significantly higher in esophageal carcinoma, head and neck cancer, lung adenocarcinoma, lung squamous cell carcinoma, and stomach adenocarcinoma and lower in kidney chromophobe, kidney renal clear cell carcinoma, kidney renal papillary carcinoma, thyroid carcinoma, and uterine corpus endometrial carcinoma tissues compared with that in adjacent normal tissues (Figure 1) (Supplementary Figure 1). The gene discussed is ERLIN2; the disease is head and neck cancer.