INS and Insulin resistance: Comparing biochemical profiles of Hypo and NoHypo groups, there were no differences in fasting glucose, HbA1c levels and surrogate measures for beta cell function (HOMA2-B), hepatic insulin sensitivity (HOMA2-S) and peripheral insulin resistance (HOMA2-IR) (p>0.05, Table 1), which were also within the normal physiological intervals (28).