LGI1 and autosomal dominant epilepsy with auditory features: Moreover, Leucine-Rich Glioma-Inactivated 1 (Lgi1) mutant rats, a model of human autosomal dominant lateral temporal lobe epilepsy (ADLTE), showed reduced astrocytic Kir4.1 expression in specific regions, including both the lateral and medial temporal lobes, after the acquisition of audiogenic seizure susceptibility (Table 1) (96).