Acute exercise also induced enrichment in gene sets related to actin/tubulin folding, which cross-talks to many hypertrophic signaling pathways (i.e., MAPK/FGFR1/2) linked to dilated and hypertrophic cardiomyopathy (Caporizzo et al., 2019), as well as IQGAPs, PAKs, and AMPK activation (see section “Discussion”) (Hedman et al., 2015; Daskalopoulos et al., 2016). This evidence concerns the gene FGFR1 and hypertrophic cardiomyopathy.