IL4 and infection: The animals that received carrageenan injection treated with MFS showed higher levels of IL-4, which inhibits chemotaxis and migration of neutrophils (Saleem et al., 1998; Impellizzieri et al., 2019) to the point that systemic inhibition of IL-4 increases the influx of CD11b+Ly6G+ cells (neutrophils) during infection (Woytschak et al., 2016).