NFE2L2 and gastric ulcer: For example, 4 was reported to activate Nrf2/ARE pathway in response to oxidative stress, inflammation and DNA damage in neurons (Liu et al., 2016), liver (Pan et al., 2016), gastric ulcer models (Mahmoud-Awny et al., 2015) as well as hematopoietic cells (Zhang et al., 2015).