VEGF is a growth factor that is involved in numerous retinal pathologies, such as proliferative diabetic retinopathy (Gupta et al., 2013), diabetic macular edema (Penn et al., 2008), etc. HGF plays an important role in ocular angiogenesis and in neuroprotection of retinal tissue. The gene discussed is HGF; the disease is diabetic macular edema.