The results showed that there were 9 active components acting on key targets such as VEGFA, VWF, IL6, TNF, NFKB1, respectively, as well as regulating signaling pathways such as AGE-RAGE, FA, Toll-like receptor, PI3K/Akt, NF-κB, apoptosis and cancer signaling pathways. This evidence concerns the gene TNF and cancer.