Another lysosomal storage disorder, Gaucher disease, has been found to not only be affected by α-syn aggregates (Manning-Bog et al., 2009; Mazzulli et al., 2011; Xu et al., 2011; Yap et al., 2011; Siebert et al., 2014), but mutations in Gaucher's causative gene (GBA1) have been identified as one of the strongest risk factors for developing PD (Sidransky et al., 2009; Bultron et al., 2010; Barrett et al., 2013; Siebert et al., 2014; Aflaki et al., 2017). Here, GBA1 is linked to Gaucher disease.