Furthermore, we knocked-down LMP1 in 2 NKTCL cell lines, HANK1 and SNK6, using shLMP1, and found that among all transcription factors only NF-κB p65 had a decreased binding ability on the PGC1β promoter (Fig. 2e). This evidence concerns the gene NFKB1 and extranodal nasal NK/T cell lymphoma.