SKP2 and hepatocellular carcinoma: Furthermore, to elucidate the effect of the lincSCRG1/miR26a/SKP2 axis on cell growth and migration in HCC, we treated SNU-387 and Hep3B cells with sh-lincSCRG1, sh-lincSCRG1 + ov-SKP2, sh-lincSCRG1 + in-miR26a and sh-NC.