In order to better understand the mechanistic role of lncRNA CBR3-AS1 in the progenesis of non-small cell lung cancers, we employed RNA pull-down assay using an in vitro transcribed CBR3-AS1 and incubated with cell lysates from A549 cells in combination with mass spectrometry (MS) analysis, aiming to detect potential CBR3-AS1 associated proteins. Here, CBR3 is linked to non-small cell lung carcinoma.