However, comparisons of clusterin AH values between groups were significantly different, with clusterin levels 1.48-fold higher in the PEXG group, 1.36-fold higher in the PEX group, and 1.41-fold higher in the POAG group compared to control subject values (p< 0.001, p< 0.001, and p< 0.001, respectively). The gene discussed is CLU; the disease is open-angle glaucoma.