Indeed in the case of RUNX1‐RUNX1T1 fusions, it is known such clones can persist for years in the absence of disease, such as in patients that have received treatment for RUNX1‐RUNX1T1‐positive AML and remained in remission despite the persistent detection of RUNX1‐RUNX1T1‐positive cells [65, 66]. This evidence concerns the gene RUNX1T1 and acute myeloid leukemia.