GRIN2B and post-traumatic stress disorder: Our findings that SDIA memory is still able to assume control of behavior after undergoing an extinction procedure that generates an extinction memory resistant to spontaneous recovery, renewal and reinstatement but sensitive to recall-induced GluN2B-containing NMDAR-dependent destabilization indicate that it is this destabilization what enables the reappearance of avoidance, and lead us to propose that blockers of these receptors might be suitable tools to prevent PTSD relapse.