ZNF154 hypermethylation was also less frequent than cancer-associated gene mutations in lung adenocarcinoma (75.7% hypermethylated versus 85.4% mutated in the common set of LUAD cancer genes), where most samples harbored either KRAS or TP53 mutations (31.9% and 41.1% respectively). This evidence concerns the gene ZNF154 and lung adenocarcinoma.