ANGPT2 and systemic lupus erythematosus: Results showed that serum Ang2 had a high ability to differentiate SLE patients from healthy individuals, by which the AUC, sensitivity and specificity for SLE patients were 0.907 (0.856–0.958), 86.21% and 85.26%, respectively, at the cutoff value of 2770.27 pg/ml (Fig. 1E).