INS and Glucose intolerance: Insulinogenic index (the difference between serum insulin 0 and 15 min after glucose infusion divided by the difference between blood glucose 0 and 15 min after glucose infusion) representing β-cell function which was reduced in hIAPP+ mice on HFD (Fig. 5f), was also significantly improved by MSL-7 (Fig. 5f), suggesting that improved pancreatic β-cell function could explain amelioration of glucose intolerance of hIAPP+ mice on HFD by MSL-7 treatment.