Infection with VACV deletion mutants ΔA49, ΔB13, and ΔB15, which lack molecules that inhibit NF-ĸB, caspase-1, and IL-1, respectively, did to provoke DC migration (Supplemental Fig. 3), revealing, at least, that deletion of these specific molecules from VACV could not rescue the migration phenotype observed in our model. Here, IL1A is linked to infection.