It is worth noting that, according to our current set of analyses, AD-associated genetic variants ADAMTS1 rs2830500, BZRAP1-AS1 rs2526378, and CELF1 rs3740688 might affect the mechanisms involved both in brain amyloidosis and neurodegeneration, implying the commonalities or convergence in function. This evidence concerns the gene TSPOAP1 and Alzheimer disease.