Molecular genetics studies have identified more than 80 genomic loci involved in about 30% of psoriasis heritability, which show variation associated with risk of disease [6] Like several other multifactorial autoimmune disorders, psoriasis manifests strong associations with HLA, mostly with HLA-C, in particular with the HLA-C*06:02 allele, which was the first risk allele identified for psoriasis, presenting certain differences amongst different races [5,7]. This evidence concerns the gene HLA-C and psoriasis.