Moreover, the expression levels of PRC2 components, including the enhancer of zeste homologue 2 (EZH2), polycomb repressive complex 2 subunit (SUZ12), and polycomb protein EED, were inversely correlated with those of CD4, CD8, and Th1-type chemokines in human CRC tissues. Here, CD8A is linked to colorectal carcinoma.