By multivariate Cox analysis, the relation between survival and GDF-15 remained significant for high risk tertile (HR 2.29 CI95% (1.24–4.24), p = 0.009) after adjusting by age (HR 1.07 CI95% (1.04–1.09), p < 0.001), history of coronary artery disease (HR 2.2 CI95% (1.26–3.82), p = 0.005), censored graft loss (HR 1.95 CI95% (1.23–3.09), p = 0.005), and other organ solid transplants (HR 2.64 CI95% (1.32–5.28), p = 0.006). This evidence concerns the gene GDF15 and coronary artery disorder.