The median relative expression of FFAR1, FFAR2, and FFAR3 was higher in esophageal biopsies obtained from patients with GERD than in respective HCs; however, statistical significance was reached only for FFAR3 (979 (203–1705) vs. 543 (210–2780) for FFAR1, 552 (76–2205) vs. 337 (141–1361) for FFAR2, 1030 (161–2732) vs. 197 (28–435) for FFAR3 (p < 0.05)) (Figure 1). Here, FFAR3 is linked to gastroesophageal reflux disease.