In this regard, it has been shown that in a mouse model of diabetic neuropathy, BM-MSCs inhibited multiple parameters of neuroinflammation, preventing the production of proinflammatory cytokines, such as IL-1β and TNF-α, and increasing the secretion of anti-inflammatory cytokines such as IL-10 and TGF-β [73]. The gene discussed is IL1B; the disease is diabetic neuropathy.