In addition, T2D rats exhibited high (p < 0.01) levels of glycosylated-hemoglobin, lactate dehydrogenase (LDH), creatine kinase (CK), urea, uric acid, creatinine, C-reactive protein, and advanced glycation end products (AGEs) in the sera as compared to the normal control group (Table 1). This evidence concerns the gene CRP and type 2 diabetes mellitus.