In contrast, Myr (300 mg/kg) treatment reciprocated diabetes-provoked increase in the levels of TNF-α (p < 0.01), IL-1β (p < 0.01), and IL-6 (p < 0.05) in the renal tissue homogenate of T2D rats as compared to T2D control animals (Figure 11a). The gene discussed is TNF; the disease is type 2 diabetes mellitus.