Although the Drosophila genome contains no orthologue of the human C9orf72 gene, Drosophila models for ALS/FTD associated with C9orf72 have been established by expressing the expanded 30 GGGGCC repeats with a CTCGAG interruption (iGGGGCC). The gene discussed is C9orf72; the disease is frontotemporal dementia.