After the analysis of the abstracts referring to genetic testing or LDLR, APOB and PCSK9 variants in FH patients, 27 articles were selected, of which 25 contained data on the LDLR, APOB, and PCSK9 variants, including three of previously published articles by our group [6,7,8,9,10,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39]. The gene discussed is PCSK9; the disease is familial hyperaldosteronism.