APOB and familial hyperaldosteronism: Mutations in one of the three genes (low-density lipoprotein receptor gene (LDLR), apolipoprotein B gene (APOB) and proprotein convertase subtilisin/kexin type 9 gene (PCSK9)) cause both HeFH and HoFH, and these genes account for the vast majority of genetically confirmed cases of FH [1].