ETV6-PDGFRβ fusions: over 32 fusion genes involving the PDGFRβ have been discovered and ETV6-PDGFRβ represents the most frequent translocation t(5;12)(q33;p13) [30,35] found in eosinophilia associated with CML [67]. The gene discussed is PDGFRB; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.