ANXA5 and melanoma: Correlating with caspase activation in the melanoma cells was a significant increase in annexin-V-positive staining in HuR-NP-treated MeWo cells at 24 h (16% increase over controls) and 48 h (12% increase over controls), respectively, compared to C-NP-treated and untreated cells (Figure 4B; p < 0.05).