A study from Ray et al. [38] revealed that plasmacytoid DCs (pDCs), which play an important role in MM cell growth and prolonged survival, express PD-L1 at higher levels as compared with MM PCs, and the blockade of PD-L1/PD-1 interactions between pDC–T cell/NK cells inhibits MM proliferation. Here, CD274 is linked to Miyoshi myopathy.