Specifically, the way in which PD-L1 soluble levels predict treatment response and progression-free survival (PFS) in newly diagnosed MM patients has been described [57]; moreover, high PD-L1 soluble levels have been associated with shorter overall survival (OS) rates and worse responses after autologous stem cell transplantation (ASCT) in MM patients [58]. Here, CD274 is linked to Miyoshi myopathy.