Montalbano et al. [79] observed oligomeric forms of MSI1 and MSI2 in the cytoplasm and in the nuclei of cortical neurons of AD, ALS (amyotrophic lateral sclerosis), and FTD (frontotemporal dementia) patients, where they were localized with oligomeric species of tau. The gene discussed is MSI2; the disease is frontotemporal dementia.