11 genes showed a negative direction of Wald ratio effect indicating a relationship between decreased gene expression and increased schizophrenia risk (FTCDNL1, FURIN, AC243562. 2, AC105749. 1, PCCB, PTPRU, THOC7, LINC02210, GATAD2A, FAM85B and FAM86B3P). The gene discussed is FAM86B3P; the disease is schizophrenia.