Univariate analysis demonstrated that HCT (odds ratio [OR], 0.908; 95% CI, 0.842–0.980; p = .013), APACHE II score (OR, 1.420; 95% CI, 1.134–1.776; p = .002), and serum sPD‐1 level on Day 3 (OR, 1.013; 95% CI, 1.005–1.021; p = .002) were significantly associated with ICs of AP (Table 2). The gene discussed is HOXD13; the disease is alkaline phosphatase measurement.