LTA4H and meningeal tuberculosis: The zebrafish findings suggested that either deficiency or excess of leukotriene A4 hydrolase (LTA4H), a key enzyme that regulates the balance of pro- and anti-inflammatory eicosanoids, increase susceptibility to TBM for opposite reasons - too little or too much inflammation (Tobin et al., 2012; Tobin et al., 2010).