MFN2 and Leber hereditary optic neuropathy: None of the category groups of age of onset of symptoms (child versus adult onset AD-CMT2A), variant topology (GTPase domain variants versus non-GTPase domain variants) or the biological effect of certain variants on mitochondrial fusion dynamics (hypofusion versus hyperfusion variants) had statistically significant enrichment with cases of CMT2A and concurrent optic atrophy.