We therefore sought to investigate the association of sST2 with platelet activation and monocyte tissue factor (TF) expression in 316 patients undergoing elective angioplasty and stenting for cardiovascular disease, and its ability to predict ischemic outcomes following infrainguinal angioplasty with stent implantation in 104 PAD patients within this cohort. This evidence concerns the gene TF and peripheral arterial disease.