No significant difference appeared in frequencies of eczema (39.3% vs. 43.3%), atopic eczema (24.0% vs. 25.1%), allergic rhinitis (20.7% vs. 19.1%), or asthma (13.0% vs. 14.1%) between groups. However, less IgE-associated allergic disease occurred in cesarean- delivered children receiving probiotics (24.3% vs. 40.5%; odds ratio, 0.47; 95% CI, 0.23% to 0.96%; P 5.035). Here, IGHE is linked to allergic rhinitis.