IL2 and perianal Crohn disease: 9 patients of perianal Crohn's disease were also treated perioperatively with adjuvant therapy, while only 1 patient was treated with both infliximab and interleukin-2. A total of 5 patients were receiving prednisone and or Imuran at the time of the surgery. Metronidazole was used perioperatively in 9 patients, and 2 patients were concomitantly treated with ciprofloxacin.