Cellular experiments of colony formation assays showed that the restoration of LATS1/2 expression abrogated the tumor-promoting effects of miR-429 as that miR-429-mediated promotion of cell proliferation was markedly suppressed by cooverexpression of LATS1/2 in RKO and HCT116 cells compared to those with the vector controls (Figures 5(d) and 5(f)). Here, LATS1 is linked to neoplasm.