As the key downstream mediator of the Hippo signaling pathway, YAP/TAZ (Yes-associated protein and its transcriptional coactivator with PDZ-binding motif) have been reported to be activated and functions as potential oncogenes in multiple cancer types such as oral squamous cell carcinoma [7], glioma [8, 9], bladder cancer [10], liver cancer, breast cancer, and lung cancer. Here, YAP1 is linked to cancer.