IGF1 and acromegaly: In acromegaly patients, serum asprosin levels were negatively correlated with the course of acromegaly (r = −0.273, P=0.026), IGF-1 SDS (r = −0.295, P=0.016), GH-Nadir (r = −0.249, P=0.046), GH-AUC (r = −0.285, P=0.021), and Cr (r = −0.415, P=0.001), while they were positively correlated with TC (r = 0.614, P < 0.001) and LDL-C (r = 0.560, P < 0.001).