Migratory breast, pancreatic, lung and colon cancer cells at TMEM overexpress an invasive form of Enabled (Ena)/vasodilator-stimulated phosphoprotein (VASP) protein (MENAINV) in their non-invasive compartments with an intact basement membrane (100) and promotes cancer invasion and migration of tumor cells (101, 102). This evidence concerns the gene VASP and cancer.