A very recent GWAS preprint by Genetics of Mortality in Clinical Care (GenOMICC) collaborators including HGI (https://genomicc.org) reported additional novel loci (DPP9, TYK2, OAS gene cluster, IFNAR2, CCR2, CCR3, HLA-G, CCHCR1, and NOTCH4) associated with COVID-19 severity, all of which contain genes with roles in immune response and/or immune-mediate diseases (Table 1) (33). Here, TYK2 is linked to COVID-19.