CRP and thrombophilia: The pathophysiology of increased risk of cerebrovascular disease during COVID-19 infection is likely multifactorial. Common abnormal laboratory test results in patients include elevated leukocyte count, C-reactive protein level, D-dimer level, ferritin level, and lactate dehydrogenase level. 81 Severe cases are characterized by elevated inflammatory markers and hypercoagulability compared with moderate cases and with increased likelihood of stroke.